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Multi-location (regional) delivery

Coordinated delivery across multiple organisations

The majority of CRDCs can deliver studies using multi-location (hub-and-spoke or regional) models, where multiple organisations work together to deliver a single study.

This allows studies to be delivered at scale across large geographical areas, different settings and populations.

How the model works

  • A central or “hub” organisation provides coordination, oversight and specialist expertise
  • Locations or “Spoke” sites deliver study activity, which could be across primary, secondary, specialist or community care
  • One organisation holds the Clinical Trial Agreement (CTA) and coordinates delivery

Different locations may deliver different study components, depending on study requirements.

Why this model is used

This approach supports:

  • Recruitment at scale and/or pace
  • Consistent delivery across multiple locations
  • Access to broader and more diverse patient populations
  • Integration of research into routine care
  • Accessibility of research to more communities

Support from the Network

The CRDC UK Network supports sponsors to:

  • Identify when a multi-location model is appropriate
  • Navigate delivery across organisations
  • Coordinate engagement and implementation

We provide practical support and coordination throughout, helping sponsors work through this model with confidence.

Contact us

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